Dietary Supplements and COVID-19: Are there any benefits?

Written by Iona Hudson

Over the past year or so, many of us have experienced changes in our dietary patterns. Market research has shown that since the beginning of the COVID-19 pandemic there has been a sharp rise in the use of dietary supplements in the UK and around the world, with consumers aiming to support their immune system (1,2,3). In the UK, 71.2% of adults are now taking dietary supplements, with vitamin D and vitamin C being the most popular (4).

It’s unclear whether dietary supplements play a role in reducing the risk of COVID-19.

Current studies have found no evidence that vitamin C, garlic or zinc have any benefits in terms of preventing or treating COVID-19, although there have been modest associations between intakes of probiotics, multivitamins, vitamin D and omega-3 and a lower risk of testing positive for the virus (5,6). However, these associations were only found in women, not men, and are based on self-reported observational data; further controlled trials are needed to clarify these associations. There has been much discussion about the benefits of vitamin D for COVID-19, although this has not yet been confirmed by scientific evidence, with mixed findings from observational studies (6,7,8). Consequently, there have been no government recommendations on dietary supplements for the prevention or treatment of COVID-19.

Nevertheless, a benefit of increased supplement intakes is that more people have been taking vitamin D than before the pandemic (4). This is especially important due to the increased time spent indoors, reducing our exposure to the sunlight needed for vitamin D production. Vitamin D plays an important role in many metabolic pathways and is essential for bone health. To meet vitamin D requirements, UK guidelines recommend a daily 10 μg vitamin D supplement over the winter months or when spending increased time indoors, yet mean intakes are below the recommendations for all age groups except women aged 65-74 years (9,10). Therefore, despite the benefits for COVID-19 being unclear, the fact that more people are taking vitamin D is extremely useful for enabling people to meet requirements.

Furthermore, whether it’s due to boredom, comfort eating or fewer trips to the supermarket, being stuck at home for months on end during the pandemic has, for many of us, led to a shift towards less varied balanced diets, including consuming more processed foods and snacks, and fewer fresh fruits and vegetables (11,12,13,14). Therefore, increased intakes of dietary supplements may have benefits for supporting people to meet vitamin and mineral requirements in a time when eating habits have changed. However, as their name suggests, supplements are intended to complement rather than compensate for a balanced diet; consuming supplements instead of eating a diet that includes fruit, vegetables, and wholegrains can have negative consequences in terms of intakes of fibre and other important nutrients. So it’s important to note that we should not rely on supplements for vitamin and mineral intakes and instead aim to get these from a balanced diet.

Overall, based on the available evidence so far, it’s unlikely that dietary supplements play a major role in terms of preventing or treating COVID-19. Despite this, increases in supplement intakes are likely to have had other COVID-19 related benefits, including raising vitamin D levels in people who have spent more time indoors, and helping people who have altered their dietary patterns during lockdown to meet their micronutrient requirements.


  1. Evans, J. (2020). Rise in vitamin sales during pandemic a tonic for consumer goods groups. Financial Times.

  2. Hamulka, J., Jeruszka-Bielak, M., Górnicka, M., Drywień, M. E., & Zielinska-Pukos, M. A. (2020). Dietary Supplements during COVID-19 Outbreak. Results of Google Trends Analysis Supported by PLifeCOVID-19 Online Studies. Nutrients, 13(1), 54.

  3. Pérez-Rodrigo, C. et al. (2021). Patterns of Change in Dietary Habits and Physical Activity during Lockdown in Spain Due to the COVID-19 Pandemic. Nutrients, 13(2), 300.

  4. Health of the Nation Survey 2021: Lockdown Focus

  5. Thomas, S. et al. (2021). Effect of High-Dose Zinc and Ascorbic Acid Supplementation vs Usual Care on Symptom Length and Reduction Among Ambulatory Patients With SARS-CoV-2 Infection: The COVID A to Z Randomized Clinical Trial. JAMA network open, 4(2), e210369.

  6. Louca, P. et al. (2021). Modest effects of dietary supplements during the COVID-19 pandemic: insights from 445 850 users of the COVID-19 Symptom Study app. BMJ Nutrition, Prevention & Health.

  7. Vimaleswaran, K. S., Forouhi, N. G., & Khunti, K. (2021). Vitamin D and covid-19. BMJ, 372.

  8. Adams, K. K., Baker, W. L., & Sobieraj, D. M. (2020). Myth busters: Dietary supplements and COVID-19. Annals of Pharmacotherapy, 54(8), 820-826.

  9. NHS (2020). Vitamin D.

  10. Public Health England. (2020). NDNS: Results from years 9 to 11 (2016 to 2017 and 2018 to 2019). Retrieved from

  11. Ruíz-Roso, M. B. et al. (2020). Changes of Physical Activity and Ultra-Processed Food Consumption in Adolescents from Different Countries during Covid-19 Pandemic: An Observational Study. Nutrients, 12(8), 2289.

  12. Giacalone, D., Frøst, M. B., & Rodríguez-Pérez, C. (2020). Reported changes in dietary habits during the COVID-19 lockdown in the danish population: The danish COVIDiet study. Frontiers in Nutrition, 7

  13. Huber, B.C., Steffen, J., Schlichtiger, J., & Brunner, S. (2020) Altered nutrition behavior during COVID-19 pandemic lockdown in young adults. European Journal of Nutrition.

  14. Bennett, G., Young, E., Butler, I., & Coe, S. (2021). The impact of lockdown during the COVID-19 outbreak on dietary habits in various population groups: A scoping review. Frontiers in Nutrition, 8

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